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Citrix vs Windows 365

Carisa Stinger | September 19, 2025

Introduction

Both Citrix DaaS and Windows 365 deliver virtual desktops, but they do so through fundamentally different models that impact cost, flexibility, and management. This guide provides a direct comparison to help you determine which platform best aligns with your technical requirements and business objectives.

Disclaimer: Content referencing Citrix and Microsoft products is based on public information from those company’s websites, current as of the last article update. For the latest product details and further inquiries, please consult the official Citrix or Microsoft websites.

What are the key differences between Citrix and Windows 365?

Before diving into technical specifications, let’s understand the core philosophy behind each platform. Their primary difference lies in their approach to delivering virtual desktops: one offers a highly customizable toolkit, while the other provides a streamlined, all-in-one product.

The table below gives you a quick reference of the differences across 7 aspects. We delve deeper into these topics in the following sections.

  Citrix DaaS Windows 365
Core Concept A flexible toolkit to build custom virtual desktop environments. A streamlined product offering a complete, managed Cloud PC.
Architecture Hybrid/Multi-Cloud. A central cloud control plane manages resources you host on Azure, AWS, GCP, or on-premises. Microsoft Cloud Native. Fully hosted and managed by Microsoft within Azure, integrated with Microsoft Intune.
Performance Protocol Citrix HDX. Highly optimized for challenging networks, high-end graphics, and specialized peripherals. Microsoft RDP. Optimized for knowledge worker productivity and deep integration with the Windows OS.
Desktop Model Flexible. Supports both persistent (dedicated) and non-persistent (pooled/shared) desktops. Persistent Only. Every user is assigned their own dedicated, personalized Cloud PC.
Security & Control Granular. Offers deep, granular policy controls for every aspect of the user session; ideal for complex compliance. Integrated. Leverages the Microsoft security stack (Entra ID, Intune, Defender) for unified endpoint management.
Cost Model Consumption-Based. You pay for Citrix licenses plus the underlying cloud infrastructure costs, which vary with usage. Fixed Monthly Fee. A predictable, all-inclusive per-user, per-month license that covers compute and storage.
Ideal Use Cases Complex hybrid/multi-cloud enterprises, demanding graphics workloads, and cost-sensitive call center/task worker scenarios. Organizations standardized on Microsoft 365, prioritizing simplicity, budget predictability, and fast deployment for knowledge workers.

At its core, Citrix DaaS (Desktop as a Service) is a flexible and powerful virtualization toolkit. This is the company's cloud-hosted offering, distinct from the traditional, on-premises managed Citrix Virtual Apps and Desktops solution. Citrix DaaS gives you granular control to build a tailored virtual desktop and application environment using a wide variety of infrastructure, including on-premises data centers or any major public cloud.

However, Citrix is not the only flexible toolkit available. Microsoft's Azure Virtual Desktop (AVD) is a powerful, cloud-native alternative that also provides a highly customizable environment for virtual desktops and applications. While AVD's flexibility offers great power, platforms like Nerdio simplify its management, automate deployment, and dramatically reduce Azure costs through advanced autoscaling. 

How to switch from Citrix to AVD >

In contrast, Windows 365 Cloud PC is a complete, Microsoft-managed SaaS product. It is designed for simplicity and predictability, delivering a dedicated, persistent Windows desktop experience directly from the cloud with a fixed monthly cost. Think of it as an enterprise-grade appliance: powerful, integrated, and ready to use.

Why are IT leaders switching to AVD?

This guide explains why AVD with Nerdio is the best answer to the Citrix challenge.

How do the core architectures compare?

The underlying architecture of each solution dictates its flexibility, management requirements, and integration capabilities. Understanding how they are constructed helps you anticipate the technical resources and expertise needed to deploy and maintain them.

What is the architecture of Citrix DaaS?

The Citrix architecture is designed for maximum flexibility, separating the management components from where your actual desktops run. This allows you to integrate with diverse and complex IT environments.

  • Control Plane: The management and control functions are hosted in Citrix Cloud, which orchestrates user connections, licensing, and administration.
  • Resource Location: You have complete freedom of choice. Your virtual desktop workloads (VDAs) can be located in any public cloud like Azure, AWS, or GCP, or within your own on-premises data centers using hypervisors like VMware vSphere or Microsoft Hyper-V.
  • Key Components:
    • Cloud Connectors: These lightweight agents are installed in your resource locations to create a secure communication channel back to the Citrix Cloud control plane.
    • Citrix Gateway Service: A cloud-hosted service that provides secure external access, it allows end-users to connect to their resources through the Citrix Workspace application, which can reduce reliance on a traditional corporate VPN for this specific access scenario.
    • HDX Protocol: A suite of proprietary technologies that optimizes the delivery of the user session, ensuring a high-performance experience even over challenging network conditions.

What is the architecture of Windows 365?

The Windows 365 architecture is built for simplicity and deep integration with the Microsoft ecosystem, with all components hosted and managed by Microsoft.

  • Control Plane: The entire management plane is integrated into the Microsoft Intune admin center, providing a familiar interface for IT admins already managing physical endpoints.
  • Resource Location: Your virtual desktop workloads (VDAs) can be located in any public cloud like Azure, AWS, or GCP, or within your own on-premises data centers; however, feature availability and requirements can differ, so it is best to consult the official Citrix documentation for platform-specific capabilities.
  • Key Components:
    • Relationship to AVD: While Windows 365 is a distinct SaaS offering, it is built upon foundational components of the Azure Virtual Desktop infrastructure to ensure secure, global connectivity.
    • Direct Azure Network Integration: Cloud PCs can be provisioned on a Microsoft-hosted network or connected directly to your own Azure virtual network (vNet), enabling access to on-premises resources.
    • Remote Desktop Protocol (RDP): User sessions are delivered using Microsoft's RDP, which is highly optimized for the Windows experience.

Which platform offers better performance and user experience?

Performance is not just about speed; it's about delivering a seamless and responsive end-user experience that makes a virtual desktop feel identical to a local one. The user's perceived experience is heavily influenced by the protocol used to transmit the desktop session and the type of desktop being delivered.

How does Citrix optimize the user experience?

Citrix is widely recognized for its high-performance HDX protocol, which is engineered to handle a vast range of use cases and network conditions.

  • Superior Protocol Performance: HDX excels in environments with low bandwidth or high latency, making it ideal for organizations with a distributed global workforce.
  • Advanced Peripheral Support: It offers robust, out-of-the-box support for specialized peripherals like document scanners, 3D mice, and dictation microphones.
  • Graphics and Media Optimization: HDX provides specific optimizations for graphically intensive applications (CAD, video editing) and real-time unified communications like Microsoft Teams and Zoom.

How does Windows 365 handle performance?

Windows 365 delivers a strong and reliable performance for mainstream knowledge worker tasks, leveraging the native integration of its protocol with the Windows operating system.

  • RDP Optimizations: Microsoft’s RDP performance is highly efficient for standard office productivity applications and has been significantly improved with enhancements like RDP Shortpath, which provides a more direct, lower-latency connection.
  • Seamless Microsoft 365 Experience: Performance is optimized for the Microsoft 365 Apps suite, ensuring a smooth user experience within that ecosystem.
  • Predictable Performance: Because each user gets a dedicated Cloud PC, performance is consistent and not impacted by other users ("noisy neighbor" problem).

What about session persistence?

This is a key philosophical and technical difference that directly impacts both user experience and cost.

  • Windows 365 (Persistent): Every user is assigned a dedicated, persistent Cloud PC. This means their data, settings, and installed applications remain intact between sessions, just like a physical PC. This provides a highly personalized and consistent experience.
  • Citrix (Persistent or Non-Persistent): Citrix gives you the choice. You can provide persistent desktops similar to Windows 365, or you can use non-persistent desktops. Non-persistent desktops are created from a master image and reset to a pristine state every time a user logs off, which is ideal for call centers, training labs, or task-based workers. This model can dramatically reduce storage costs and simplify management.

Take Windows to the Cloud with Microsoft and Nerdio

Join us for a webinar to discover how to take Windows to the cloud. Get insights from industry leaders on navigating the modern workspace and driving secure, cloud-powered operations.

What are the differences in security and control?

For any enterprise, security and administrative control are non-negotiable, especially when enabling a flexible hybrid work strategy. Both platforms offer robust security, but they provide different levels of granularity and integrate with different management toolsets.

What security features does Citrix provide?

Citrix offers a defense-in-depth approach with highly granular policy controls that allow you to lock down the user environment completely.

  • Granular Policy Engine: Control everything from clipboard access and printer redirection to whether a user can save files to their local drive.
  • Advanced Security Features: Includes capabilities like session watermarking to deter data theft, an app protection policy that prevents screen scraping and keylogging, and security analytics to detect anomalous user behavior.
  • Architectural Isolation: Keeps corporate data and applications isolated within the data center or cloud, reducing the risk of data leakage to unmanaged endpoints.

What is the security model for Windows 365?

Windows 365 leverages the powerful, integrated Microsoft security stack, making it a natural fit for organizations already standardized on Microsoft technologies.

  • Zero Trust Integration: Natively integrates with Microsoft Entra ID (formerly Azure AD) for identity and Conditional Access policies.
  • Unified Endpoint Management: Cloud PCs are managed through Microsoft Intune, allowing you to apply the same security baselines, compliance policies, and endpoint protection configurations to both your physical and virtual PCs.
  • Microsoft Defender for Endpoint: Cloud PCs can be onboarded to Microsoft Defender for Endpoint, a comprehensive platform that provides preventative protection, post-breach detection, and automated investigation and response capabilities.

How do the costs and licensing models differ?

Understanding the Total Cost of Ownership (TCO) is critical, and the two platforms have fundamentally different pricing models. Windows 365 offers cost predictability, while Citrix provides cost flexibility that can be optimized for specific use cases.

Citrix DaaS Windows 365
Pricing Model Consumption-based. You pay for Citrix licenses + underlying cloud infrastructure. Fixed, predictable per-user/per-month fee.
Includes Citrix software licenses. Compute, storage, and data transfer (within limits).
Additional Costs All Azure/AWS/GCP infrastructure costs (compute, storage, networking). On-prem network connectivity, enhanced security licenses.
Best For Cost optimization via autoscaling, non-persistent desktops, and multi-cloud hosting. Budget predictability, simplified purchasing.

How is Windows 365 priced?

Windows 365 is sold as a fixed-price license per user, per month. This price includes the Azure compute, storage, and some data transfer associated with the Cloud PC. This simple, predictable model makes budgeting straightforward, as costs do not fluctuate with user activity.

How is Citrix DaaS priced?

Citrix pricing is more complex and based on consumption. You pay for two main things:

  1. Citrix DaaS Licenses: A subscription fee per user or per device.
  2. Infrastructure Consumption: The actual cost of the cloud resources (VMs, storage, data egress) your desktops consume on Azure, AWS, GCP, or your on-premises hardware.

While this model is more complex, it offers significant opportunities for cost optimization, especially when paired with autoscaling technologies that can power on VMs when needed and shut them down when inactive.

Take Windows to the Cloud with Microsoft and Nerdio

Join us for a webinar to discover how to take Windows to the cloud. Get insights from industry leaders on navigating the modern workspace and driving secure, cloud-powered operations.

Which use cases are best suited for each platform?

The best choice depends entirely on your specific business needs, existing infrastructure, and user requirements. By matching your use cases to the platform's strengths, you can ensure a successful deployment.

When should you choose Windows 365?

  • Deeply invested in the Microsoft ecosystem: If you already rely on Microsoft Intune, Entra ID, and Microsoft 365, the Cloud PC offers seamless integration.
  • Need for simplicity and fast deployment: If you already rely on Microsoft Intune, Entra ID, and Microsoft 365, the Cloud PC offers your IT team seamless integration in deployment.
  • Require budget predictability: The fixed monthly cost eliminates billing surprises and simplifies financial planning.
  • Users require a persistent, personalized desktop: Ideal for knowledge workers, developers, and executives who need a consistent environment that functions like a traditional PC. These Cloud PCs are typically provisioned with Windows 11 Enterprise, which provides a familiar user interface along with advanced security and management features designed for corporate environments.

When is Citrix a better fit?

  • Operating in a hybrid-cloud or multi-cloud environment: If your applications and data are spread across on-premises data centers and multiple clouds, Citrix provides a unified fabric to deliver them.
  • Supporting demanding, high-performance use cases: For engineers using CAD software, designers on Adobe Creative Suite, or traders using financial modeling tools, the HDX protocol provides superior performance.
  • Needing non-persistent desktops: For call centers, healthcare kiosks, or student labs where users don't need a personalized desktop, non-persistent VDI can dramatically lower your TCO.
  • Requiring granular security and policy control: For industries with stringent compliance requirements like finance or government, Citrix offers unparalleled control over the user session.

Citrix to AVD: Step-by-step migration guide

How can you simplify the deployment and management of these platforms?

While powerful, both Windows 365 and Citrix introduce management complexities, particularly in large-scale enterprise environments. As you scale, you will face challenges with image management, cost control, user provisioning, and performance monitoring.

This is where third-party management and automation platforms provide significant value by unifying administration and optimizing costs. Platforms like Nerdio Manager for Enterprise are built to sit on top of these services, providing a single administrative console to overcome common challenges. Such platforms can deliver value in several key areas:

  • Unified Administration: Manage your Windows 365 Cloud PCs and complex Citrix DaaS or Azure Virtual Desktop environments from a single pane of glass, reducing administrative overhead.
  • Advanced Cost Optimization: Implement sophisticated autoscaling logic for VDI environments to dramatically reduce Azure infrastructure spending by matching resources to real-time user demand.
  • Simplified Image Management: Streamline the creation, testing, and deployment of desktop images across your entire virtual desktop fleet.
  • Automated Provisioning: Automate the entire lifecycle of users and desktops, from onboarding new employees to reclaiming licenses, freeing up valuable IT resources.

See this demo to learn how you can optimize processes, improve security, increase reliability, and save up to 70% on Microsoft Azure costs1.

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About the author

Photo of Carisa Stinger

Carisa Stinger

Head of Product Marketing

Carisa Stringer is the Head of Product Marketing at Nerdio, where she leads the strategy and execution of go-to-market plans for the company’s enterprise and managed service provider solutions. She joined Nerdio in 2025, bringing 20+ years of experience in end user computing, desktops-as-a-service, and Microsoft technologies. Prior to her current role, Carisa held key product marketing positions at Citrix and Anthology, where she contributed to innovative go-to-market initiatives. Her career reflects a strong track record in driving growth and adoption in the enterprise technology sector. Carisa holds a Bachelor of Science in Industrial Engineering from the Georgia Institute of Technology.

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